Updated Info on Auvi-Q Epinephrine Injectors

I have been informed that Auvi-Q will not be distributing their epinephrine injectors until the first quarter of 2013.

From the company's PR rep:

"Sanofi has been working hard the past two months to build ample supply of the device to meet the anticipated demand for the product and to help ensure nationwide distribution...manufacturing is occurring following FDA approval to help ensure that when a patient or caregiver does fill a prescription for Auvi-Q, he or she receives a product with an adequate expiration date."

For additional information on this new product, check out the Auvi-Q site. From there you can watch a demo and sign up to be informed when the product becomes available.

There will soon be an alternative to the familiar EpiPen...and this new one talks you through the injection process. Stay tuned.

AllergySense Helps Train Professionals in Food Allergies

Put expired EpiPens® and Twinject® to good use this month. Throughout the month of May, AllergySense will send expired pens to allergists' offices for training purposes.

Of course, I always recommend training yourself and family members by using an expired pen in an orange.

However, if you have several old pens lying around,mail them in a padded envelope to AllergySense for distribution. You'll even be entered to win great prizes.

Hurry, offer ends May 31, 2010.

Food Allergic Should Have Double Dose of Epinepherine Available

So the latest recommendation is that people with food allergies should be carrying two doses of their life-saving epinephrine. This is the conclusion of researchers at Children's Hospital Boston after a six year study. Dr. Rudders headed the study and says, "Until we're able to clearly define the risk factors for the most severe reactions, the safest thing may be to have all children at risk for food-related anaphylaxis carry two doses of epinephrine".

It was also discovered during the course of this research that many emergency rooms are treating food allergy reactions with antihistamines and steroids, rather than epinephrine. Rudders explains that "these findings may be due to lack of a universal understanding of anaphylaxis in the ED (emergency department) before 2006". She goes on to say that she hopes her study will move things forward in this area.

The entire study was written up in the April 2010 journal of Pediatrics.

New Injector of Epinephrine

The EpiPen® has long been the standard prescription for patients who may suffer from anaphylaxis due to food insect and other allergies.

Several years ago a new device for delivering epinephrine came out, the Twinject®. The advantage of this device was that each unit contained two doses. Patients have long been cautioned that epinephrine doses only last 15-20 minutes, so Twinject touted its advantage as giving the patient an additional back-up dose and more time to seek treatment.

Sciele Pharmaceuticals is soon releasing a new epinephrine device called Adrenaclik. It, like the Epipen, is a single dose injector. Actually it looks much like the EpiPen and the instructions for use are similar, although with the Adrenaclik, two gray caps need to be pulled off from either end, rather than one on the Epipen.

I wonder if we will see more of these auto-injectors? I wonder if that means the price will come down? It's pretty expensive to have several on-hand, isn't it? I did find documentation that states the EpiPen patent doesn't expire until Sept. 2025. I don't understand all the legalese on patents and generic drugs. Anyone else?

Food Allergy Reactions

Do you carry more than one dose of epinephrine in the event of an allergic reaction?

A recent study shows certain risk factors associated with the need for more than one dose. One surprise...a history of asthma does not appear to be one of those risk factors.

People requiring more than one dose tend to be younger and tend to present with wheezing, cyanosis (bluish/purplish tinge to the skin), arrhythmias (abnormal heart rhythms), nausea, vomiting and shock. Those who present with hives are less likely to require a second dose.

Check out the full abstract and think about whether more than one dose of epinephrine is right for you or your child.